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Abstract: This research aims to develop an electrode carbon paste/molecularly imprinted polymer (MIP) as a sensor for the analysis of creatinine by potentiometric. The preparation of a non-imprinted polymer (NIP) is done by mixing aniline, creatinine, and potassium peroxodisulfate with mole ratio of 2:0.1:1. Creatinine is extracted from the polymer using hot water to form mold creatinine, this so-called MIP. In this study, the optimum electrode has a composition made of activated carbon, paraffin, and MIP of 40:35:25 (mass ratio), pH of working solution 6, and response time of 91 - 192 s. The Nernst factor obtained from this study was 23.2 mV/decade, the measuring range of 10-6 - 10-3 M, lower detection limit of 5.49 x 10-6 M, and the upper detection limit of 1.07 x 10-3 M. The accuracy of methods for concentration of 10-6 - 10-3 M was 76.40 - 165.80%, and the precision expressed by the coefficient of variation for the concentration is 0.05 - 0.32%. The electrodes have up to 83 times of usage. Urea does not interfere with the performance of the electrode carbon paste MIP on the analysis of creatinine
Template and target information: creatinine
Author keywords: creatinine, molecularly imprinted polymer, Carbon paste, Potentiometric