MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Ye L, Mosbach K
Article Title: Molecularly imprinted microspheres as antibody binding mimics.
Publication date: 2001
Journal: Reactive and Functional Polymers
Volume: 48
Issue: (1-3)
Page numbers: 149-157.
DOI: 10.1016/S1381-5148(01)00050-5
Alternative URL: http://www.che.utexas.edu/research/biomat/PDFReprints/ReactivePolymers_48_149-157(2001).pdf

Abstract: Molecular imprinting is an emerging technique for preparing artificial antibodies that have potential applications in affinity-based separations, biomimetic sensors and assays. The conventional imprinting methods either deliver a monolith that is mechanically ground to irregular particles - a time- consuming process with low yield, or involves complicated polymerization process by which spherical beads may be obtained, but with frequently compromised binding specificity. We have recently developed a novel molecular imprinting method that can deliver microspheres bearing imprinted binding sites, quickly, cleanly and in good yield. Imprinted uniform microspheres are synthesized by precipitation polymerization of a dilute solution of functional monomer and crosslinker in the presence of a print molecule. The method is generally applicable to a large variety of target molecules. For the first time, an enzyme probe is successfully used in a competitive herbicide assay using molecularly imprinted microspheres as the affinity adsorbents. (C) 2001 Elsevier Science B.V. All rights reserved
Template and target information: theophylline, 17β-estradiol, E2, 2,4-D, 2,4-dichlorophenoxyacetic acid


  Mug featuring the name Klaus spelled out in symbols of the chemical elements  Lab Honey Periodic table mug    mug featuring the template Estradiol

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner