MIPdatabase
Authors: Zhou X, Gao XX, Song FY, Wang CP, Chu FX, Wu SS
Article Title: A sensing approach for dopamine determination by boronic acid-functionalized molecularly imprinted graphene quantum dots composite.
Publication date: 2017
Journal: Applied Surface Science
Volume: 423
Page numbers: 810-816.
DOI: 10.1016/j.apsusc.2017.06.199
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0169433217318548
Abstract: A novel fluorescence sensor was developed for dopamine (DA) determination based on molecularly imprinted graphene quantum dots and poly(indolylboronic acid) composite (MIPs@ PIn-BAc/GQDs). When the DA is added to the system, it leads to an aggregation and fluorescence quenching of the MIPs@ PIn-BAc/GQDs because of the covalent binding between the catechol group of DA and boronic acid. Such fluorescence behaviors are used for well testing DA in a range from 5 x 10-9 to 1.2 x 10-6 M with the detection limit of 2.5 x 10-9 M. Furthermore, the prepared sensors could well against the interferences from various biomolecules and be successfully used for the assay of DA in human biological samples, exhibiting excellent specificity. It is believed that the prepared MIPs@ PIn-BAc/GQDs hold great promise as a practical platform that can monitor DA level change
Template and target information: dopamine, DA
Author keywords: Graphene quantum dots, Molecularly imprinted polymers, DA, fluorescent, sensor
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