MIPs logo MIPdatabase      MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Hu Y, Huang W, Tong YK, Xia QF, Tian MM
Article Title: Boronate-affinity hollow molecularly imprinted polymers for the selective extraction of nucleosides.
Publication date: 2017
Journal: New Journal of Chemistry
Volume: 41
Issue: (15)
Page numbers: 7133-7141.
DOI: 10.1039/C7NJ00148G

Abstract: Boronate-affinity hollow molecularly imprinted polymers (h-MIPs) were prepared and applied to the selective enrichment of four nucleosides in traditional Chinese medicine injection samples, followed by HPLC detection. The synthesis mechanism of the h-MIPs was studied. Due to a large amount of boronic acid groups were introduced by 3-aminophenylboronic acid (APBA) in the outermost polymer shell of the MIPs, which was of great importance for improving the enrichment efficiency of the nucleosides. Furthermore, owing to the hollow structure of the h-MIPs, more binding cavities were located on the inner and outer surfaces of the h-MIPs, which could facilitate the removal of template molecules from the polymers and the rebinding of the target molecules to the polymers. Under optimal conditions, the detection limits of the four nucleosides were in the range of 0.012-0.033 μg mL-1. At the different spiked levels, the recoveries of the nucleosides were in the range of 63.8-108.9%. The proposed method was successfully applied to determine four nucleosides in five injection samples. The boronate-affinity h-MIPs provided a promising selective enrichment platform for precise nucleoside analysis
Template and target information: nucleosides


  mipdatabase.com logo imprinters do it in bulk shirt  Science Teacher peptide mug  Perpetual student shirt

Molecules Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon