Abstract: This study synthesized a new glial fibrillary acidic protein (GFAP)-imprinted polymer based on the principle of biomimiking. A carbon electrode printed using an imprinted polymer-modified screen was constructed under "grafting-to" modification for the detection of the GFAP. Then the atomic force microscopy and scanning electron microscopy assays were employed for the characterization of the decorated surface, with the limit of detection (LOD) of 0.04 μg/mL obtained under aqueous circumstance. The GFAP determination was further investigated in human blood serum to confirm the methodology and effect of the developed sensor.
Template and target information: protein, glial fibrillary acidic protein, GFAP
Author keywords: Glial fibrillary acidic protein, molecularly imprinted polymer, Nervous system, Electrochemical determination, Human blood serum