MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Liu Y, Shen T, Hu L, Gong H, Chen CY, Chen XM, Cai CQ
Article Title: Development of a thermosensitive molecularly imprinted polymer resonance light scattering sensor for rapid and highly selective detection of hepatitis A virus in vitro.
Publication date: 2017
Journal: Sensors and Actuators B: Chemical
Volume: 253
Page numbers: 1188-1193.
DOI: 10.1016/j.snb.2017.07.166
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0925400517313801

Abstract: In this study, a thermosensitive imprinted polymer coating SiO2 was developed for a resonance light scattering (RLS) thermosensitive virus-affinity sensor, which exhibited high selectivity for virus monitoring. In this sensor, N-isopropylacrylamide was a temperature-sensitive element. The recognition performance of the nanosensor for viruses was regulated by temperature control for the specific capture of the target virus at 40 C, resulting in the increase of RLS intensity and its release at 20 C. Moreover, the RLS intensity of the nanosensor significantly increased within 30 min. Accordingly, a very good detection limit of 1.1 pmol L-1 was obtained. The nanosensor was successfully used to detect the additional hepatitis A virus from a dilution of human serum, and recoveries in the range of 90.8% to 108.3% were attained at three spiking levels of viruses. Overall, this study addressed the problems of high nonspecific adsorption and long duration of detection process. Furthermore, a facile, rapid, and efficient tool for virus detection was provided
Template and target information: viruses, hepatitis A virus
Author keywords: Thermo-sensitive, Virus molecularly imprinted polymers, Resonance light scattering, Specific detection


  Eat, sleep, imprint, repeat greetings card  SMI logo mug  Man of proper-tea mug in blue

Molecules Special Issue call      Appeal for information






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon