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Abstract: Herein we report a sensor array based on quartz crystal microbalance (QCM) to simultaneously detect two biomarkers, namely low-density lipoprotein (LDL), and high-density lipoprotein (HDL). Selective recognition takes place through molecularly imprinted polymers (MIP) with both MIPs and corresponding non-imprinted polymer (NIP) as reference electrode. Sensor array performs highly appreciably in term of selectivity to LDL and HDL (defined through its cholesterol LDL-C, and HDL-C) when operated in 10 mM PBS. The sensor response time is less than 15 min. Furthermore, coefficients of variation indicating precision of our sensor array are at 2%-8%
Template and target information: protein, lipoprotein, low-density lipoprotein, LDL, high-density lipoprotein, HDL
Author keywords: lipoproteins sensor array, low-density lipoprotein, high-density lipoprotein, molecularly imprinted polymer, quartz crystal microbalance