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Reference type: Journal
Authors: Liu YJ, Bao JJ, Zhang L, Chao C, Guo JJ, Cheng YC, Zhu YJ, Xu GJ
Article Title: Ultrasensitive SERS detection of propranolol based on sandwich nanostructure of molecular imprinting polymers.
Publication date: 2018
Journal: Sensors and Actuators B: Chemical
Volume: 255
Page numbers: 110-116.
DOI: 10.1016/j.snb.2017.08.018
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0925400517314417

Abstract: Propranolol (PRO) is a β-blocker used in the treatment of heart disease. Recently, it has become a kind of organic pollutions due to its wide-spread use. However, the reliable and rapid analytical method for detection and monitoring PRO is still a challenge. We design a novel sandwich nanostructure for the specific and sensitive determination of trace propranolol in complex samples by surface enhanced Raman scattering technology. The sandwich nanostructure consists of graphene oxide/molecular imprinting polymers, target molecules, and sliver nanoparticles. This novel approach exhibits excellent sensitivity for propranolol, which makes the limit of detection as low as 10-11 mol/L. The results reveal the exceptional potential of the sandwich structure for high-performance environmental monitoring
Template and target information: propranolol, PRO
Author keywords: Surface-enhanced Raman scattering, propranolol, molecular imprinting polymers, Sandwich nanostructure, Silver nanoparticles

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