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Reference type: Journal
Authors: Abass AM, Ahmed A
Article Title: Synthesis and application of trimethoprim selective electrodes.
Publication date: 2017
Journal: Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences
Volume: 3
Issue: (2)
Page numbers: 146-156.
Alternative URL: http://rjlbpcs.com/wp-content/uploads/2017/July-Aug/14.Dr_.Ahmed-Ahmed-.pdf

Abstract: This research establishes a comparative study stuck between three constructed liquid electrodes for influence trimethoprim(TMP) using direct potentiometric in various pharmaceutical preparations. TMP selective electrodes were depended on ion-pair: Trimethoprim-Molybdophsophoric acid in PVC matrix membrane with plasticizers, di-butyl phthalate(DBPH), o-nitro phenyl octyl ether(o-NPOE), tri-butyl phosphate(TBP). Electrodes were gave slopes (58.61,58.41,15.30 mV/decade), respectively, with linear ranges were about(1.2 x 10-5 - 1.0 x 10-2, 6.1 x 10-5 - 1.0 x 10-2 and 2.5 x 10-5 - 1.0 x 10-2 M), respectively. Lifetime was (45, 1, 2 days), respectively. The best limit of detection was 2.5 x 10-6M for trimethoprim membrane based on DBPH. Also were studied selectivity coefficient, and PH effect.
Template and target information: trimethoprim
Author keywords: trimethoprim, liquid selective sensors, Trimethoprim determination

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