MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Zhang Q, Liu C, Wang SY, Lv YK
Article Title: Determination of tetracycline veterinary drug residues in milk powder by on-line solid phase extraction coupled with high performance liquid chromatography with molecularly imprinted monolithic column.
Publication date: 2017
Journal: Journal of Food Safety and Quality
Volume: 8
Issue: (7)
Page numbers: 2692-2697.
Alternative URL: http://www.chinafoodj.com/ch/reader/view_abstract.aspx?file_no=20170420004&flag=1

Abstract: Objective To establish a preparation method of molecularly imprinted polymer monolithic column (MIP-MC) with the high cross-linking structures, and determine the tetracyclines residues in milk powder by on-line solid-phase extraction coupled with high performance liquid chromatography (SPE-HPLC). Methods The MIP-MC was prepared in a stainless steel column using oxytetracycline as the template, methacrylic acid and hydroxyethyl methacrylate as functional monomers, ethylene glycol dimethacrylate and dipentaerythritol hexaacrylate as the cross-linking agent, azobisisobutyronitrile as initiator, and acetone-methanol-dodecanol as porogenic solvent. The obtained monolith was applied to the determination of tetracycline drugs residues in milk powder by SPE-HPLC. Results An enrichment factor of 19.3 along with a good sample clean-up effect was obtained under optimum on-line solid phase extraction conditions. The recoveries of tetracyclines at 0.05, 0.25 and 0.5 mg/kg were in the range of 84.2%~103.4% with the relative standard deviation of 1.37%~4.87%. The limits of detection (S/N=3) and quantitation (S/N=10) of the proposed methods were 8.48~11.74 mg/kg and 28.24~39.09 mg/kg, respectively. Conclusion The on-line solid phase extraction method is simple, rapid and highly sensitive, and it is suitable for the determination of tetracyclines antibiotics residues in milk powder.
Template and target information: oxytetracycline, tetracyclines


  mipdatabase.com logo imprinters do it in bulk shirt  Science Teacher peptide mug  Perpetual student shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner