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Reference type: Journal
Authors: Yawari I, Kaykhaii M
Article Title: Determination of (S)-warfarin using an activated screen printed gold electrode modified with gold nanoparticles and an enantioselective molecularly imprinted polymer.
Publication date: 2017
Journal: Analytical Methods
Volume: 9
Issue: (46)
Page numbers: 6583-6589.
DOI: 10.1039/C7AY02031G

Abstract: In this work a novel and simple electrochemical sensor for the determination of (S)-warfarin based on an activated screen printed gold/Au nanoparticles/molecularly imprinted polymer electrode (ASPG/AuNPs/MIP) was introduced. Cyclic voltammetry, differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy were used to investigate the electrochemical behavior of (S)-warfarin at the modified electrode under optimum conditions. According to the results, ASPG/AuNPs/MIP showed a linear range for (S)-warfarin concentrations from 5.0 nM to 1.0 μM and a limit of detection of 1.0 nM by DPV. The proposed sensor was used for the determination of (S)-warfarin in commercial tablets, human serum and urine with satisfactory results
Template and target information: (S)-warfarin, warfarin


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