MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Zheng WH, Zhao M, Liu WF, Yu SM, Niu LT, Li GG, Li HF, Liu WL
Article Title: Electrochemical sensor based on molecularly imprinted polymer/reduced graphene oxide composite for simultaneous determination of uric acid and tyrosine.
Publication date: 2018
Journal: Journal of Electroanalytical Chemistry
Volume: 813
Page numbers: 75-82.
DOI: 10.1016/j.jelechem.2018.02.022
Alternative URL: https://www.sciencedirect.com/science/article/pii/S1572665718301061

Abstract: This work reported a molecularly imprinted polymer (MIP)/reduced graphene oxide (RGO) composite for simultaneous determination of uric acid and tyrosine. The MIP layer was electropolymerized on the RGO modified electrode using a novel monomer of 2-amino-5-mercapto-1,3,4-thiadiazole and the dual template of uric acid and tyrosine. The integration of MIP with RGO resulted in the regular nanostructure and large surface area of the sensing interface. The sensing mechanism of the sensor can be explained by first recognizing the target molecules and then catalyzing the oxidation reactions on the MIP/RGO composite. The electrochemical behavior of uric acid and tyrosine on the MIP/RGO composite was evaluated. Influencing factors, including the electropolymerization scanning cycles, monomer/template ratio, and pH values were optimized. Under the optimal condition, the sensor exhibits wide linear ranges for uric acid (0.01 μM - 100 μM) and tyrosine (0.1 μM - 400 μM) with detection limits of 0.0032 μM and 0.046 μM, respectively. In addition, this MIP/RGO composite was applied to detect uric acid and tyrosine in serum and urine samples
Template and target information: dual template, uric acid, tyrosine
Author keywords: molecularly imprinted polymer, Reduced graphene oxide, 2-amino-5-mercapto-1,3,4-thiadiazole, uric acid, tyrosine


  Template of Doom spoof movie poster bag  Chemistry peptide mug  Chemists are fun customisable shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner