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Abstract: With the goal of improving the affinity and specificity in molecularly imprinted polymers, metal complexing polymer matrices capable of specific recognition and binding to metal - coordinating substrates have been prepared by molecular imprinting technology. The synthesis of these materials involves preorganization of 4 - vinylpyridine as monomer, with copper - 2,2' - dipyridyl as template, and subsequent polymerization with a large excess of ethylene glycol dimethacrylate as the cross - linking agent. The characteristics of its substrate binding selectivities and specificities to the template was investigated in details. Scatchard analysis demonstrated that two kinds of binding site were formed in the imprinted polymers. Their dissociation constants were estimated to be 30 μmol/L and 0.45 mmol/L, respectively. Factors that influenced rebinding of the imprinted polymer including the concentration of copper (II) acetate, the kind of cation and anion, were explored. The results show that the selective recognition of copper - 2, 2' - dipyridyl by the polymer was distinctly enhanced at the optimum concentration of copper (II) acetate, as compared with the control polymer with the same chemical composition. Finally, the substrate selectivity of imprinted polymer and non- imprinted polymer was investigated
Template and target information: copper-2,2'-dipyridyl