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Reference type: Journal
Authors: Zhong N, Byun HS, Bittman R
Article Title: Hydrophilic cholesterol-binding molecular imprinted polymers.
Publication date: 2001
Journal: Tetrahedron Letters
Volume: 42
Issue: (10)
Page numbers: 1839-1841.
DOI: 10.1016/S0040-4039(01)00045-4

Abstract: Novel hydrophilic molecularly imprinted polymers (MIPs) were prepared using acryloyl-containing hydrophilic monomers (including cholesteryl acrylate (CA) and acryloyl-6-amino-6- deoxy-beta (or gamma)-cyclodextrin). and their steroid-binding properties were analyzed in 2-PrOH by HPLC. The MIPs bound 38- 50 mu mol of cholesterol/g, while the corresponding nonimprinted control polymers (containing no CA) bound only 6-9 mu mol cholesterol/g. The sterol-binding selectivity was illustrated with estrone, which was bound by MIPs in the range 5-36 mu mol/g. (C) 2001 Elsevier Science Ltd. All rights reserved


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