Abstract: Sensitivity is an important parameter of molecularly imprinted electrochemical sensors, and various methods have been extensively investigated to improve this parameter. This review focuses on recent reports about different methods that can enhance the sensitivity of these sensors. To a great extent, the sensitivity of the molecularly imprinted sensor is limited by the number of cavities formed in a molecularly imprinted polymer on an electrode after elution. To enhance sensitivity and fabricate sensing devices, researchers employ signal amplification by labels, amplification by functional materials doped in imprinted membranes, sensitive film amplification, and other methods. Some perspectives in this research area, current problems, and challenges are also outlined
Template and target information: Review - MIPs in electrochemical sensors
Author keywords: Molecularly imprinted electrochemical sensor, Sensitivity enhancement, strategy, nanoparticles, Enzyme amplification, gate-controlled effect