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Reference type: Journal
Authors: Lowdon JW, Alkirkit SMO, Mewis RE, Fulton D, Banks CE, Sutcliffe OB, Peeters M
Article Title: Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers.
Publication date: 2018
Journal: Analyst
Volume: 143
Issue: (9)
Page numbers: 2002-2007.
DOI: 10.1039/C8AN00131F
Alternative URL: https://www.researchgate.net/publication/324491127_Intelligently_Designed_Molecularly_Imprinted_Polymers_MIPs_for_the_Selective_Extraction_and_Quantification_of_the_Novel_Psychoactive_Substance_NPS_Methoxphenidine_and_its_Regioisomers

Abstract: In this communication, we present the first developed Molecularly Imprinted Polymers (MIPs) for the specific detection of a New Psychoactive Substance (NPS); namely, methoxphenidine (MXP) and its regioisomers. Selectivity of the MIP towards MXP is studied by analysing mixtures and an acquired street sample with High Performance Liquid Chromatography coupled to UV detection. The study demonstrates that the engineered polymers selectively extract MXP from heterogeneous samples, which makes for a very powerful diagnostic tool that can detect traces of MXP in complicated NPS samples
Template and target information: methoxphenidine, MXP


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