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Reference type: Journal
Authors: Wu DF, Hu XL, Wang CL, Cui LJ
Article Title: Preparation of thymopentin molecularly imprinted polymers on SiO2 and recognition characteristics.
Publication date: 2014
Journal: Journal of Functional Materials
Volume: 45
Issue: (14)
Page numbers: 14133-14139.
Alternative URL: https://www.researchgate.net/publication/287234895_Preparation_of_thymopentin_molecularly_imprinted_polymers_on_SiO2_and_recognition_characteristics

Abstract: The functional monomer of methylacrylic acid (MAA) and acrylamide (AM) were evaluated using computer simulation technological, the MAA was selected as functional monomer. By coupling action of 3-methacryloxypropyl trimethoxysilane (MPS), polymethylacrylic acid (PMAA) was grafted on the surface of silica particles. Using solution polymerization method, the molecular imprinted polymer Tp5-MIP was obtained using PMAA/SiO2 as vector, thymopentin as the template molecular and ethylene glycol dimethacrylate (EDMA) as the crosslinking agent. Both static and dynamic binding properties of Tp5-MIP for thymopentin were studied. Result shows that Tp5-MIP exhibits excellent binding affinity and specific selectivity for the template molecule. The recognition resulted from the imprinting process.
Template and target information: thymopentin, Tp5
Author keywords: silica gel, surface imprinting, molecularly imprinted polymer (Tp5-MIP), molecular recognition, thymopentin (Tp5)


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