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Reference type: Journal
Authors: Betlem K, Down MP, Foster CW, Akthar S, Eersels K, Van Grinsven B, Cleij TJ, Banks CE, Peeters M
Article Title: Development of a Flexible MIP-Based Biosensor Platform for the Thermal Detection of Neurotransmitters.
Publication date: 2018
Journal: MRS Advances
Volume: 3
Issue: (28)
Page numbers: 1569-1574.
DOI: 10.1557/adv.2017.634
Alternative URL: https://www.researchgate.net/publication/322272574_Development_of_a_Flexible_MIP-Based_Biosensor_Platform_for_the_Thermal_Detection_of_Neurotransmitters

Abstract: We have developed high affinity Molecularly Imprinted Polymers (MIPs) for neurotransmitters such as dopamine, noradrenaline and caffeine. These polymer particles are mixed within the bulk of screen-printed ink allowing masss-producible bulk modified MIP Screen-Printed Electrodes (MIP-SPEs) to be realised. We have explored different SPE supporting surfaces, such as polyester, tracing paper and household-printing paper. The performance of those MIP-SPEs is studied using the Heat-Transfer Method (HTM), a patented thermal method. With the combination of screen-printing techniques and thermal detection, it is possible to develop a portable sensor platform that is capable of low-cost and straightforward detection of biomolecules on-site. In the future, this unique sensor architecture holds great promise for the use in biomedical devices
Template and target information: dopamine, noradrenaline, caffeine
Author keywords: sensor, polymer, biomimetic (chemical reaction)


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