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Reference type: Journal
Authors: Yang YT, Wu CY, Liu WL, Shi JL, Zhou J, He FY
Article Title: Chinese medicine preparation supramolecular imprinting templates based on in vitro release characteristics of BYHW sustained-release tablet.
Publication date: 2016
Journal: China Journal of Chinese Materia Medica
Volume: 41
Issue: (6)
Page numbers: 1040-1045.
Alternative URL: http://caod.oriprobe.com/articles/48167742/Chinese_medicine_preparation_supramolecular_imprinting_templates_based.htm

Abstract: The study focused on the in vitro release of Buyanghuanwu (BYHW) elementary osmotic pump sustained release tablets. Its band similarity was calculated by the total quantum statistical moment. Meanwhile, in vitro release characteristics were analyzed to discuss the existence of supramolecular imprinting templates. The results show that the same imprint templates may exist in different structures of traditional Chinese medicine (TCM)'s multi-components. The BYHW sustained release tablets prepared by elementary osmotic pump can meet the objectives of "overall control, synchronous release". However, the supramolecular imprinting templates in TCM compound prescriptions should be further explored, the overall and synchronous release of different components was controlled through imprinting templates, so as to seek the more suitable sustained release preparation technology for multiple components of TCM, and make it in line with the characteristics of TCM.
Author keywords: Buyanghuanwu, Supramolecules, imprinting template, sustained release, overall control


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