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Reference type: Book Chapter
Authors: Saranya R, Murugan R, Hegde M, Doyle J, Babu R
Publication date: 2018
Chapter title: Affinity Membranes for Capture of Cells and Biological Substances.
Page numbers: 175-195.
DOI: 10.1007/978-3-319-78163-1_8

Book title: Filtering Media by Electrospinning: Next Generation Membranes for Separation Applications
Editors: Focarete ML, Gualandi C, Ramakrishna S
Publisher: Springer International Publishing
City: Cham
ISBN: 978-3-319-78163-1

Abstract: Fundamental approaches of developing electrospun affinity membranes and their applications in cell capture and separation of biologically active substances are discussed. Basic principles of affinity membrane-based separation process and types of various surface modifications are described, to produce electrospun affinity nanofibers for filtration or fractionation of desired biological substances. The relevant advancements in electrospinning for novel surface modifications have been discussed with a special focus on coupled ligands and molecular imprinted polymers. Applications pertaining to cell capturing and filtration of biomolecules are reviewed in detail, with reference to recent reports on electrospun affinity nanofiber membranes for various antibody and protein purification
Template and target information: Review - affinity membranes
Author keywords: affinity membranes, electrospinning, ligands, nanomaterials, Nanofibers, immobilization, Biomolecule, filtration, Cell capture


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