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Reference type: Journal
Authors: Uchiyamada K, Okubo K, Asakawa K, Kamon Y, Kitayama Y, Takeuchi T, Suzuki H
Article Title: Directional Coupler Biosensor with Molecularly Imprinted Polymer.
Publication date: 2018
Journal: Sensors and Materials
Volume: 30
Issue: (5)
Page numbers: 1009-1017.
DOI: 10.18494/SAM.2018.1815
Alternative URL: http://myukk.org/SM2017/sm_pdf/SM1558.pdf

Abstract: A microfabricated directional coupler (DC) was used for the label-free, real-time detection of proteins. As an alternative to biomolecules such as antibodies, molecularly imprinted polymer (MIP) was used. With human serum albumin (HSA) as a model analyte, distinct responses were observed. On the other hand, the sensor did not respond to bovine serum albumin (BSA). Also, with a nonimprinted polymer (NIP), no responses were observed for HSA. The MIP could be regenerated, and responses of the same sensor after three cycles of measurement and regeneration gave similar values.
Template and target information: protein, human serum albumin, HSA
Author keywords: directional coupler, silicon nitride waveguide, molecularly imprinted polymer (MIP), human serum albumin (HSA)

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