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Reference type: Journal
Authors: Zhang LL, Zhu CC, Chen CB, Zhu SH, Zhou J, Wang ML, Shang PP
Article Title: Determination of kanamycin using a molecularly imprinted SPR sensor.
Publication date: 2018
Journal: Food Chemistry
Volume: 266
Page numbers: 170-174.
DOI: 10.1016/j.foodchem.2018.05.128
Alternative URL: https://www.sciencedirect.com/science/article/pii/S030881461830952X

Abstract: A kanamycin molecular imprinted SPR sensor was prepared with 4-vinylbenzeneboronic acid as the functional monomer, polyethylene glycol acrylate and 2,2'-azo isobutyl amidine hydrochloride as the crosslinker and the initiator, respectively. Under optimum conditions, the response performance of the imprinted SPR sensor to kanamycin was evaluated. The imprinted sensor had a better imprinting effect and selectivity for kanamycin than the non-imprinted one. The linear range of imprinted sensor for kanamycin was from 1.0 x 10-7 to 1.0 x 10-5 mol/L (R2 = 0.9941). Based on a signal-to-noise ratio of 3, the detection limits of kanamycin were 4.33 x 10-8 mol/L for milk powder and 1.20 x 10-8 mol/L for honey, with the RSD as 1.18% and 0.31%, respectively
Template and target information: kanamycin
Author keywords: Kanamycin, molecularly imprinted polymer, surface plasmon resonance


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