MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Liu Q, Wan JF, Cao XJ
Article Title: Synthesis of core-shell molecularly imprinted polymers (MIP) for spiramycin I and their application in MIP chromatography.
Publication date: 2018
Journal: Process Biochemistry
Volume: 70
Page numbers: 168-178.
DOI: 10.1016/j.procbio.2018.04.001
Alternative URL: http://www.sciencedirect.com/science/article/pii/S1359511317317750

Abstract: Spiramycin I is a main component of spiramycin and a structural analogue of neospiramycin I, which is an impurity in spiramycin production. Molecular imprinting technology (MIT) has many advantages in selectivity and environmental compatibility in biomolecular separation. In this study, core-shell molecularly imprinted polymers (MIPs) were prepared for spiramycin I. Methyl methacrylate (MMA) was used to prepare the seed core, and acrylamide (AM)/methacrylic acid (MAA) was chosen to prepare the shell. The structure of polymerized MIPs was successfully characterized by transmission electron microscopy, dynamic light scattering, Fourier transform infrared spectroscopy and elemental analysis. The adsorption results showed that MIPs polymerized by different monomers exhibited very different adsorption for spiramycin I. MIPs with monomeric AM achieved a fast mass transfer, high adsorption capacity and high selectivity. Then, these MIPs were applied to separate spiramycin I from the fermentation broth in the chromatographic column, and its recovery and purity were 61% and 83%, respectively. Finally, regeneration of the MIP chromatographic column was studied to explore its recycling performance in application
Template and target information: spiramycin I
Author keywords: Spiramycin I, Core-shell molecularly imprinted polymers, selectivity, Chromatographic column


  Meitnerium periodic table mug  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner