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Reference type: Journal
Authors: Diltemiz SE
Article Title: Development of MIP-based QCM Sensors for Determination of Hyaluronic Acid (HA).
Publication date: 2018
Journal: Hacettepe Journal of Biology and Chemistry
Volume: 46
Issue: (2)
Page numbers: 273-283.
DOI: 10.15671/HJBC.2018.235
Alternative URL: http://hjbc.hacettepe.edu.tr/index.php/hjbc/article/view/97

Abstract: In this study, quartz crystal microbalance (QCM) based recognition systems have been developed for the determination of hyaluronic acid (HA). For this purpose, firstly; N-methacryloyl-l-tyrosine (MAT), MAT-D-Glucuronic acid (MAT-D-GA) and MAT-Cu(II)-D-Glucuronic acid (MAT-Cu(II)-D-GA) pre-organized monomers have been synthesized, and characterized. Then, D-glucuronic acid active sites of HA biomacromolecule have been imprinted on QCM sensor surface to create HA selective binding sites. In the last step, the binding interactions, usabilities in recognition and determination of prepared sensors have been investigated.
Template and target information: hyaluronic acid, HA
Author keywords: Hyaluronic acid, MIP-QCM, MIP, quartz crystal microbalance, Molecularly imprinted polymers

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