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Abstract: The coupling technique of molecular imprinting with surface enhanced Raman scattering is regarded as a promising analysis method due to its properties of high sensitivity and selectivity. However, the traditional molecular imprinting technique is very difficult to thoroughly remove template molecules. So, the technique will result in strong background interference impacting the test results when it is combined with the surface-enhanced Raman scattering spectroscopy. In this study, the Ag particles were first synthesized adopting the method of ascorbic acid reduction. Then, the as-prepared Ag particles were silanized using 3-methacryloxypropyltrimethoxysilane. Finally, the dummy molecularly imprinted polymers were synthesized using abietic acid replacing malachite green as the template molecule to react with methacrylamide functional monomer. The results show that the resulting "core-shell" composite substrate has a more remarkable SERS enhancement than Ag substrate. And its detection limit for malachite green can down to 10-11 mol/L. This method can eliminate the background interference and improve the accuracy of the analysis results, which provide a new method for the ultrasensitive detection of organic dyes.
Template and target information: dummy template, abietic acid, malachite green, MG
Author keywords: Dummy molecularly imprinted polymer, Surface-enhanced Raman scattering, Malachite green, Ag particles