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Reference type: Journal
Authors: Momeneh H, Gholivand MB
Article Title: Mycophenolate mofetil sensor based on molecularly imprinted polymer/multi-walled carbon nanotubes modified carbon paste electrode.
Publication date: 2018
Journal: Analytical Biochemistry
Volume: 557
Page numbers: 97-103.
DOI: 10.1016/j.ab.2018.07.014
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0003269718303786

Abstract: Using square wave voltammetry, a carbon paste electrode modified by molecularly imprinted polymer (MIP) as a recognition element of mycophenolate mofetil (MMF) and multi-walled carbon nanotubes was used for MMF monitoring To investigate the electrode during modification, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) were utilized. After optimization of the effective parameters, the anodic peak current of MMF was utilized for dynamic range study which was linear in 9.9 nM-87 μM range. The detection limit of the sensor was 7.0 nM. The capture ability of MIP to target was compared with that of non-imprinted polymer (NIP). The practical application of the sensor in biological fluid samples analysis demonstrates its selectivity, sensitivity, and stability
Template and target information: mycophenolate mofetil, MMF
Author keywords: Mycophenolate mofetil, Cellcept, molecularly imprinted polymer, voltammetry, carbon paste electrode


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