MIPdatabase
Authors: Roushani M, Jalilian Z, Nezhadali A
Article Title: A novel electrochemical sensor based on electrode modified with gold nanoparticles and molecularly imprinted polymer for rapid determination of trazosin.
Publication date: 2018
Journal: Colloids and Surfaces B: Biointerfaces
Volume: 172
Page numbers: 594-600.
DOI: 10.1016/j.colsurfb.2018.09.015
Alternative URL: http://www.sciencedirect.com/science/article/pii/S092777651830626X
Abstract: A novel molecularly imprinted polymer sensor for fast and direct determination of trazosine (TR) was studied. The voltammetric sensor based on molecularly imprinted polymer (MIP) with disposable gold nanoparticles modified screen printed carbon electrode (MIP/AuNPs/SPCE) is developed for the determination of TR. Under the optimum conditions, the peak current of the sensor and TR concentration showed a good linear relationship over the range from 2.0 to 250.0 μM, with a low detection limit (S/N = 3) of 0.3 μM. The modified electrode demonstrated good electrocatalytic properties toward the oxidation of TR. This sensor selectively detected TR even in the presence of high concentration of similar compounds and MIP/AuNPs/SPCE was also confirmed successfully for the determination of TR in the various real samples including human blood serum, urine and trazosin tablet
Template and target information: trazosin, trazosine, TR
Author keywords: Trazosin, Screen printed carbon electrode, molecularly imprinted polymer, gold nanoparticles
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