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Reference type: Journal
Authors: Azzouz A, Goud KY, Raza N, Ballesteros E, Lee SE, Hong JK, Deep A, Kim KH
Article Title: Nanomaterial-based electrochemical sensors for the detection of neurochemicals in biological matrices.
Publication date: 2019
Journal: TrAC Trends in Analytical Chemistry
Volume: 110
Page numbers: 15-34.
DOI: 10.1016/j.trac.2018.08.002
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0165993618302796

Abstract: Neurochemicals such as dopamine, glutamate, GABA, adenosine, and serotonin are efficient indicators for quantifying the dynamics of many brain disorders. Both in-ávivo and in-ávitro detection strategies for those neurochemicals are important in treating various human diseases. Along with common, conventional tools (e.g., microelectrodes, biosensors, spectrophotometry, Fourier transform infrared, Raman, chromatography, fluorescence, flow injection, and capillary electrophoresis), electrochemical sensors based on nanomaterials (NMs; e.g., graphene, carbon nanotubes, molecular imprinted polymers, metal organic frameworks, and metallic nanoparticles) have emerged as potent tools for the quantitation of neurochemicals due to their robust designs, selectivity, sensitivity, precision, and accuracy. The performance of the latter varies widely because of differences in their sensing efficiencies. This review provides a brief introduction to those electrochemical sensors with a detailed overview of the latest trends, limitations of NM-based sensing techniques, and the potential for their future expansion for various neurochemicals
Template and target information: Review - electrochemical sensors for neurochemicals
Author keywords: nanomaterials, Neurochemicals, electrochemical sensors, dopamine, Molecularly imprinted polymers, Metal organic frameworks

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