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Reference type: Journal
Authors: Gültekin A, Karanfil Celep G, Say R
Article Title: Gadolinium chelate monomer based memories onto QCM electrodes for folic acid detection in commercial follow-on baby milk.
Publication date: 2018
Journal: Journal of Food Measurement and Characterization
Volume: 12
Issue: (4)
Page numbers: 2892-2898.
DOI: 10.1007/s11694-018-9904-3

Abstract: A novel folic acid-imprinted quartz crystal microbalance (QCM) nanosensor in order to detect folic acid depending on the fabrication of folic acid-imprinted polymer film on a QCM electrode was developed with methacrylamidoantipyrine-gadolinium (III) [MAAP-Gd(III)] used as a monomer for metal coordination-chelation interaction to obtain a more selective molecularly imprinted polymers (MIPs). The developed folic acid-imprinted nanosensor on the MIP/QCM detection system showed outstanding properties such as a stronger affinity of 3.07 x 10^7 M-1, a short response time of 10 min, wider linear range of 0-100 μM, a selectivity of k = 8.25 and lower detection limit of 0.0080 μM. After characterizing its all features, the newly designed folic acid-imprinted QCM nanosensor was utilized to detect folic acid level in commercial follow-on baby milk in order to determine its use in real samples
Template and target information: folic acid
Author keywords: Folic acid, Molecularly imprinted polymers, quartz crystal microbalance, Metal-chelate monomer

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