MIPdatabase
Authors: Wu XD, Cao JS, Bao SS, Shao GS, Wang ZH, Qin BY, Wang T, Fu YJ
Article Title: Preparation and application of modified three-dimensional cellulose microspheres for paclitaxel targeted separation.
Publication date: 2021
Journal: Journal of Chromatography A
Volume: 1655
Article Number: 462487.
DOI: 10.1016/j.chroma.2021.462487
Alternative URL: https://www.sciencedirect.com/science/article/pii/S0021967321006117
Abstract: In this article, we successfully prepared three-dimensional cellulose microspheres modified by molecularly imprinted polymer for paclitaxel recognition and separation (3D-CM &PTX&MIPs). The material was characterized by Fourier Transform Infrared spectroscopy (FTIR), Scanning Electron Microscope (SEM), Thermogravimetric Analysis (TG) and diffraction of X-rays (XRD). Under the optimized adsorption conditions, the maximum adsorption capacity reached 65.7 mg/g. And after 5 runs of reuse, (3D-CM&PTX&MIPs) still maintained a reusability rate of 90%. Besides, (3D-CM&PTX&MIPs) showed excellent selectivity for target PTX. Finally, (3D-CM&PTX&MIPs) was used for PTX recognition and separation in the extracts of yew leaves. This research laid a good foundation and scientific basis for the efficient, environmentally friendly, and rapid enrichment of metabolites in plants using bio-based molecularly imprinted polymers
Template and target information: paclitaxel, PTX
Author keywords: molecularly imprinted polymer, Three-dimensional cellulose microspheres, selective recognition, Paclitaxel, Taxus x media Rehde
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