MIPdatabase
Authors: Söylemez MA, Güven O
Article Title: Preparation and detailed structural characterization of Penicillin G imprinted polymers by PALS and XPS.
Publication date: 2019
Journal: Radiation Physics and Chemistry
Volume: 159
Page numbers: 174-180.
DOI: 10.1016/j.radphyschem.2019.02.050
Alternative URL: https://www.sciencedirect.com/science/article/pii/S0969806X18309022
Abstract: Template molecule selected in this study, namely penicillin G (PG) is a member of β-lactam antibiotics (BLAs) and the first antibiotic found by human and used to treat bacterial diseases. PG imprinted polymers were prepared by grafting onto PE/PP non-woven fabrics via gamma irradiation. Methacrylic acid (MAA) and ethylene glycol dimethylacrylate (EGDMA) were used as functional monomer and crosslinking agent, respectively. Non-imprinted polymers (NIP) were also synthesized using the same procedure in the absence of PG. Chemical and physical characterizations of fabrics grafted with molecularly imprinted polymers (MIP) were carried out by using FTIR-ATR, XPS, SEM and positron annihilation lifetime spectroscopy (PALS). Binding behaviour of MIP was investigated for various template concentrations. Uptake and release of template molecule were determined by HPLC. Imprinting factor IF (IF = ratio of binding to MIP/binding to NIP) was determined as 4.46 for 1.0 ppm PG solution for a 3-h incubation
Template and target information: penicillin G, PG
Author keywords: Penicillin G, Radiation induced grafting, Positron annihilation
Join the Society for Molecular Imprinting
New items RSS feed
View latest updatesSign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.
Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
