Abstract: A molecularly imprinted electrochemical sensor was developed for the detection of pefloxacin. The molecularly imprinted polymer (MIP) was prepared via electrodeposition on the surface of a gold nanoparticles/reduced graphene oxide/single-walled carbon nanotubes modified glass carbon electrode by incorporation of pefloxacin as a template molecule during the electrochemical polymerization of o-phenylenediamine. The namocomposite of gold nanoparticals/reduced graphene oxide/single-walled carbon nanotubes was obtained by one-step electrochemical reduction. Differential pulse voltammogram (DPV) showed a linear pefloxacin concentration range from 5.0 × 10-7 mol/L to 2.0 × 10-5 mol/L, and the detection limit was 1.6 × 10-8 mol/L. The sensor also showed high selectivity, stability and reproducibility. Moreover, the sensor was successfully applied in the analysis of actual milk samples with satisfactory recovery rates
Template and target information: pefloxacin
Author keywords: molecularly imprinted polymer (MIP), Electrochemical sensor, Pefloxacin, gold nanoparticles, reduced oxide graphene, single-walled carbon nanotubes