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Reference type: Journal
Authors: Wang JX, Zou LH, Xu JJ, Zhang R, Zhang HB
Article Title: Molecularly imprinted fluoroprobes doped with Ag nanoparticles for highly selective detection of oxytetracycline in real samples.
Publication date: 2021
Journal: Analytica Chimica Acta
Volume: 1161
Article Number: 338326.
DOI: 10.1016/j.aca.2021.338326
Alternative URL: https://www.sciencedirect.com/science/article/pii/S0003267021001525

Abstract: A molecularly imprinted polymer (MIP), which is synthesized by a nanomolding process around a template, has emerged as a promising analytical tool for environmental quality monitoring and food safety test. In this work, a fluoroprobe with Ag-doped MIP nanolayer (16 nm thickness) is successfully prepared for the highly selective detection of oxytetracycline (OTC) in real samples (i.e. Yangtze River water, swine urine). In the MIP nanolayer, two functional monomers (i.e. 4-(2-acrylamidoethylcarbamoyl)-3-fluorophenylboronic acid, methacrylic acid) synergistically constitute the specific recognition sites. Meanwhile, the doped Ag enhances the detection sensitivity (with a detection limit of 5.38 nM) and accelerates the detection rate (within 2.5 min) even in real samples. Therefore, the present study paves the way for the preparation of MIP-based fluoroprobes, showing great prospects in environmental quality and food safety tests
Template and target information: oxytetracycline, OTC
Author keywords: molecularly imprinted polymer, oxytetracycline, fluorescence detection, Rapid analysis, Ag nanoparticle


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