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Reference type: Journal
Authors: Chen ZD, Nagaoka T
Article Title: Recognition of vitamin K-1 with a molecularly imprinted self-assembled monolayer film.
Publication date: 2000
Journal: Bunseki Kagaku
Volume: 49
Issue: (7)
Page numbers: 543-545.
DOI: 10.2116/bunsekikagaku.49.543
Alternative URL: https://www.jstage.jst.go.jp/article/bunsekikagaku/49/7/49_7_543/_article

Abstract: In this paper, we present a novel way to design a self- assembled monolayer, based on molecular imprinting protocols, for the selective recognition of hydrophobic molecules. A monolayer of octadecanethiol, templated with n-hexadecane, was fabricated on a gold substrate, and its voltammetric behavior was examined with vitamin K-1 and K-3. The monolayer film showed a voltammetric response only to hydrophobic vitamin K-1 molecules, while a film without the hexadecane template showed neither a peak assigned to vitamin K-1 nor K-3. The results demonstrate that the present technique can be used as a simple and highly selective surface-designing tool for the fabrication of a self-assembled monolayer based electrode
Template and target information: vitamin K1


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