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Reference type: Journal
Authors: Choi JR, Yong KW, Choi JY, Cowie AC
Article Title: Progress in Molecularly Imprinted Polymers for Biomedical Applications.
Publication date: 2019
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 22
Issue: (2)
Page numbers: 78-88.
DOI: 10.2174/1386207322666190325115526

Abstract: Background: Molecularly Imprinted Polymers (MIPs), a type of biomimetic materials have attracted considerable interest owing to their cost-effectiveness, good physiochemical stability, favorable specificity and selectivity for target analytes, and long shelf life. These materials are able to mimic natural recognition entities, including biological receptors and antibodies, providing a versatile platform to achieve the desirable functionality for various biomedical applications. Objective: In this review article, we introduce the most recent development of MIPs to date. We first highlight the advantages of using MIPs for a broad range of biomedical applications. We then review their various methods of synthesis along with their latest progress in biomedical applications, including biosensing, drug delivery, cell imaging and drug discovery. Lastly, the existing challenges and future perspectives of MIPs for biomedical applications are briefly discussed. Conclusion: We envision that MIPs may be used as potential materials for diverse biomedical applications in the near future
Template and target information: review - MIPs in biomedicine
Author keywords: Molecularly imprinted polymers, antibodies, Biomedical applications, Biosensing, drug delivery, Cell imaging, drug discovery


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