MIPdatabase
Authors: Topçu AA, Özgür E, Yilmaz F, Bereli N, Denizli A
Article Title: Real time monitoring and label free creatinine detection with artificial receptors.
Publication date: 2019
Journal: Materials Science and Engineering: B
Volume: 244
Page numbers: 6-11.
DOI: 10.1016/j.mseb.2019.04.018
Alternative URL: https://www.sciencedirect.com/science/article/pii/S0921510719301035
Abstract: Molecular imprinting technique is used to design artificial creatinine receptor on the gold surface of surface plasmon resonance (SPR) chip using N-methacryloyl-(l)-histidine methyl ester (MAH), as a functional monomer. Surface characterization of SPR sensor chip is performed with atomic force microscope (AFM), ellipsometry and contact angle measurements. Creatinine imprinted SPR sensor is characterized with a linear range between 1 and 100 mM and limit of detection (LOD) and limit of quantification (LOQ) of creatinine are found 57 μM and 190 μM, respectively. N-hydroxysuccinimide (NHS) and creatine molecules are selected to examine the selectivity of creatinine imprinted SPR sensor. Reusability studies of SPR sensor is determined in urine mimic samples
Template and target information: creatinine
Author keywords: creatinine, surface plasmon resonance, molecular imprinting, artificial receptor
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