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Reference type: Journal
Authors: Wang YF, Fan J, Meng ZH, Xue M, Qiu LL
Article Title: Fabrication of an antibiotic-sensitive 2D-molecularly imprinted photonic crystal.
Publication date: 2019
Journal: Analytical Methods
Volume: 11
Issue: (22)
Page numbers: 2875-2879.
DOI: 10.1039/C9AY00674E

Abstract: A molecularly imprinted colloidal array (MICA) for the detection of clindamycin hydrochloride (CLI) was prepared by embedding a two-dimensional (2D) polystyrene crystalline colloidal array within a CLI-imprinted hydrogel. The MICA showed a significant response to CLI, in which the particle spacing of the MICA changed 41 nm within 10 min in response to 1 mM CLI, and the structural color of the MICA changed from blue, green, to yellow, and finally, to red. Furthermore, MICA was also used to detect a similar antibiotic, lincomycin, which had only induced a 10 nm change in the spacing. The MICA was reused more than 5 times. This low-cost and naked-eye sensing material provides a label-free way to detect CLI and other antibiotics
Template and target information: clindamycin hydrochloride, CLI, clindamycin

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