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Reference type: Journal
Authors: Das AAK, Medlock J, Liang H, Nees D, Allsup DJ, Madden LA, Paunov VN
Article Title: Bioimprint aided cell recognition and depletion of human leukemic HL60 cells from peripheral blood.
Publication date: 2019
Journal: Journal of Materials Chemistry B
Volume: 7
Issue: (22)
Page numbers: 3497-3504.
DOI: 10.1039/C9TB00679F

Abstract: We report a large scale preparation of bioimprints of layers of cultured human leukemic HL60 cells which can perform cell shape and size recognition from a mixture with peripheral blood mononuclear cells (PBMCs). We demonstrate that the bioimprint-cell attraction combined with surface modification and flow rate control allows depletion of the HL60 cells from peripheral blood which can be used for development of alternative therapies of acute myeloid leukaemia (AML)
Template and target information: cells, human leukemic HL60 cells


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