MIPdatabase
Authors: Luo LH, Zhang F, Chen CY, Cai CQ
Article Title: Molecular imprinting resonance light scattering nanoprobes based on pH-responsive metal-organic framework for determination of hepatitis A virus.
Publication date: 2020
Journal: Microchimica Acta
Volume: 187
Issue: (2)
Article Number: 140.
DOI: 10.1007/s00604-020-4122-1
Abstract: Molecularly imprinted polymer (HM@MIP) nanoprobes were designed form the pH-responsive polymer (dimethylaminoethyl methacrylate (DMA)) and MIL-101. This probe was applied to the selective determination of hepatitis A virus (HAV) through Resonance light scattering (RLS) technique. DMA adjusts pH of the system to facilitate the capture and release of virus by HM@MIPs as anticipated. And it results in the enhancement or weaken of RLS intensity. According to RLS intensity at 470 nm, a linear concentration of 0.02-2.0 nmol L-1 and a limit of detection of 0.1 pmol L-1 were obtained within 20 min. The excellent recoveries ranges from 88% to 107%, and it indicates the prominent ability of the HM@MIPs to determination HAV in human serum and their potential ability to determination virus in real applications
Template and target information: virus, hepatitis A virus, HAV
Author keywords: MIL-101, Resonance light scattering nanoprobe, pH- responsive polymer, Virus molecular imprinting
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