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Reference type: Journal
Authors: Li ZY, Cui ZM, Tang YW, Liu XY, Zhang XM, Liu BX, Wang XH, Draz MS, Gao X
Article Title: Fluorometric determination of ciprofloxacin using molecularly imprinted polymer and polystyrene microparticles doped with europium(III)(DBM)3phen.
Publication date: 2019
Journal: Microchimica Acta
Volume: 186
Issue: (6)
Article Number: 334.
DOI: 10.1007/s00604-019-3448-z

Abstract: The authors describe a microparticle-based system for the detection of the fluoroquinolone antibiotic ciprofloxacin. The method is using the tris(dibenzoylmethane)(1,10-phenanthroline)europium(III) luminophore in polystyrene microparticles along with a molecularly imprinted polymer (MIP) for ciprofloxacin. If ciprofloxacin is captured by the MIP, it quenches the fluorescence of the luminophores. Fluorescence drops linearly in the 0.5-100 μg L-1 ciprofloxacin concentration range, and the detection limit is 92 ng L-1. The method was applied to the analysis of fish samples to assess the analytical performance of the probe. Recoveries ranged from 85.4 to 86.6%, and relative standard deviations between 2.1 and 3.9% (for n = 5)
Template and target information: ciprofloxacin
Author keywords: Fluorometric determination, Polystyrene microparticles, molecularly imprinted polymer, Europium(III)(DBM)3Phen, Luminophore, Ciprofloxacin, Fluorescent probe, fish sample, selective recognition, Quenching


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