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Reference type: Journal
Authors: Lee MH, Thomas JL, Liu WC, Zhang ZX, Liu BD, Yang CH, Lin HY
Article Title: A multichannel system integrating molecularly imprinted conductive polymers for ultrasensitive voltammetric determination of four steroid hormones in urine.
Publication date: 2019
Journal: Microchimica Acta
Volume: 186
Issue: (11)
Article Number: 695.
DOI: 10.1007/s00604-019-3797-7

Abstract: This work reports on a modularized electrochemical method for the determination of the hormones cortisol, progesterone, testosterone and 17β-estradiol in urine. These hormones were employed as templates when generating molecular imprints from aniline and metanilic acid by electropolymerization on the surface of screen-printed electrodes. The electrically conductive imprint was characterized by SEM, AFM and cyclic voltammetry. A four-channel system was then established to enable simultaneous determination of the hormones by cyclic voltammetry. The detection limits for cortisol, progesterone, testosterone and 17β-estradiol are as low as 2, 2.5, 10 and 9 ag mL-1 (for S/N = 3)
Template and target information: cortisol, progesterone, testosterone, 17β-estradiol
Author keywords: Multichannel potentiostat, hormones, molecular imprinting, electrochemical sensing, Urine analysis

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