Reference type: Journal
Authors: Teixeira RA, Dinali LAF, Silva CF, de Oliveira HL, da Silva ATM, Nascimento CS, Borges KB
Article Title: Microextraction by packed molecularly imprinted polymer followed by ultra-high performance liquid chromatography for determination of fipronil and fluazuron residues in drinking water and veterinary clinic wastewater.
Publication date: 2021
Journal: Microchemical Journal
Volume: 168
Article Number: 106405.
DOI: 10.1016/j.microc.2021.106405
Alternative URL: https://www.sciencedirect.com/science/article/pii/S0026265X21004896

Abstract: A fast, efficient and safe method combining a low-cost lab-microextraction by packed sorbent-device and high-ultra-performance liquid chromatography with diode array detection was developed to determine fipronil and fluazuron residues in drinking water and veterinary clinic wastewater. The prepolymerization complexes of mesoporous molecularly imprinted polymer was studied by density functional theory calculations reaching Δ H = -26.7 kcal mol-1 and Δ G = -8.5 kcal mol-1, in which used fluazuron as template, methacrylic acid as monomer and acetonitrile as porogenic solvent. After, mesoporous molecularly imprinted polymer was properly characterized, demonstrating excellent selectivity to the studied analytes and high adsorbent capacity. After optimization, the better sample preparation conditions were: 75 μL of ultrapure water as washing solvent, 250 μL as methanol as eluent, 250 μL of sample at pH 7, two thaw-eject cycles and two times can be reused. After proper validation, the method was applied in the analysis of fipronil and fluazuron residues in drinking water and veterinary clinic wastewater and showed high reproducibility with relative recoveries of 98.58 ± 2.64% and 99.92 ± 1.43% for fipronil and fluazuron, respectively
Template and target information: fipronil, fluazuron
Author keywords: molecularly imprinted polymer, Microextraction by packed sorbent, pesticides, water samples