MIPdatabase
Authors: Peng C, Lan YH, Sun L, Chen XZ, Chi SS, Zheng C, Dong LY, Wang XH
Article Title: Facile Synthesis of Boronate Affinity-Based Molecularly Imprinted Monolith with Reduced Capturing pH Towards Cis-Diol-Containing Compounds.
Publication date: 2019
Journal: Chromatographia
Volume: 82
Issue: (7)
Page numbers: 1029-1040.
DOI: 10.1007/s10337-019-03736-7
Abstract: Here, we report a novel boronate affinity-based surface molecularly imprinted monolith (BA-SMIM), which was fabricated by simple two-step atom-transfer radical polymerization (ATRP) strategy. A boronate affinity-based surface non-imprinted monolith (BA-SNIM) was prepared as control. The synthesis parameters of BA-SMIM were optimized, and the resultant BA-SMIM was characterized in detailed. In both aqueous-rich and organic-rich mobile phases, the BA-SMIM could recognize cis-diol-containing compounds mainly due to the imprinting effect. The chlorogenic acid and rosmarinic acid with two cis-diols could interact synergistically with two imprinting cavities of BA-SMIM, so they retained longer on BA-SMIM than one cis-diol-containing compounds. In addition, the capturing pH reduced from 8.6 on BA-SNIM and to 7.8 on BA-SMIM for one cis-diol-containing compounds, and from 7.4 on BA-SNIM and to 7.0 on BA-SMIM for two cis-diol-containing compounds, respectively. The reducing of capturing pH value on BA-SMIM may be attributed to the nanoconfinement effect of imprinting cavity
Template and target information: cis-diols, chlorogenic acid, rosmarinic acid
Author keywords: boronate affinity, molecularly imprinting polymers, Nanoconfinement effect
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