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Reference type: Journal
Authors: Asghar N, Mustafa G, Yasinzai M, Al-Soud YA, Lieberzeit PA, Latif U
Article Title: Real-Time and Online Monitoring of Glucose Contents by Using Molecular Imprinted Polymer-Based IDEs Sensor.
Publication date: 2019
Journal: Applied Biochemistry and Biotechnology
Volume: 189
Issue: (4)
Page numbers: 1156-1166.
DOI: 10.1007/s12010-019-03049-3

Abstract: A highly sensitive, selective, reversible, and reusable glucose sensor is developed by using molecularly imprinted polymer-based artificial receptors onto interdigital transducer. Sensor receptors were synthesized through bulk imprinting technology by using styrene as monomer, ethylene glycol dimethacrylate (EGDMA) as cross-linker, and AIBN as free radical initiator. Topography of the synthesized receptors was investigated by scanning electron microscopy (SEM). Fabricated sensor showed concentration-dependent linear and reversible response with lower limit of detection of 30 ppb and upper limit of detection ~ 500 ppm. Furthermore, newly fabricated sensor is highly selective towards its analyte of interest in the presence of other competing agents, and the regeneration of sensor response has been assessed with the percentage error of less than 2% under the period of 1 year at room temperature and pressure conditions. The reported sensor may have potential technological applications in the field of medical diagnostics, food, and pharmaceutical industry
Template and target information: glucose
Author keywords: molecular imprinted polymers, electrochemical sensors, glucose, sensitivity, selectivity, Limit of detection


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