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Reference type: Journal
Authors: Zhu Y, Xu Y, Liu GX
Article Title: Electrochemical Detection of the Anesthetic Drug Procaine Hydrochloride Based on Molecularly Imprinted Polymer/Diamond-Graphite Composite Electrode.
Publication date: 2021
Journal: International Journal of Electrochemical Science
Volume: 16
Article Number: 211237.
DOI: 10.20964/2021.12.35
Alternative URL: http://www.electrochemsci.org/papers/vol16/211237.pdf

Abstract: Overdose of procaine may lead to many health problems. However, highly sensitive detection of procaine has always been a challenge. Electrochemical sensor is of great significance in the field of life and health due to its high sensitivity, low cost and compatibility with portable technology. In this work, a sensor based on diamond/graphite hybrid with a molecular imprinting membrane was developed. The sp3-bonded diamond and sp2-bonded graphite have good mechanical properties and wide potential window. The molecular imprinting membrane can be immobilized on the diamond/graphite surface for selective determination of procaine. The optimized conditions allowed the sensor to detect the procaine concentration linearly in the range of 4 × 10-8 - 2.5 × 10-5 M. The limits of detection were calculated to be 1.5 × 10-8 M.
Template and target information: procaine hydrochloride
Author keywords: procaine, Electrochemical sensor, Diamond, Graphite, Anesthetic drug

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