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Reference type: Journal
Authors: Zhang Q, Berg D, Mugo SM
Article Title: Molecularly imprinted carbon based electrodes for tetrahydrocannabinol sensing.
Publication date: 2019
Journal: Inorganic Chemistry Communications
Volume: 107
Article Number: 107459.
DOI: 10.1016/j.inoche.2019.107459
Alternative URL: https://www.sciencedirect.com/science/article/pii/S1387700319303107

Abstract: Tetrahydrocannabinol (THC) sensors were fabricated using carbon nanotubes (CNT) or carbon beads and poly(methyl acrylic acid-co- ethylene glycol dimethacrylate) (poly(MAA-Co-EGDMA)) with molecularly imprinting technology in micropipette tubes. The carbon materials allow the electrode high sensitivity due to high surface area, and the cavities of THC temples will enhance selectivity of the electrode toward THC because of molecular recognition of THC cavities. These electrodes exhibit high THC detection selectivity over caffeine and acetaminophen. The limit of THC detection for CNT-MIP electrodes is as low as 0.18 ± 0.02 ng/mL, which is much lower than that of electrodes with nonimprinted polymers (NIP) which is 12.5 ± 0.5 ng/mL. The morphology was characterized using scanning electron microscope (SEM), which exhibited the presence of polymers on the surface of carbon materials in the electrodes. The thermal stability of polymers was also tested using thermogravimetric analysis (TGA)
Template and target information: tetrahydrocannabinol, THC
Author keywords: THC molecularly imprinting polymers, THC electrochemical sensor


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