MIPdatabase
Authors: Voronin AV, Malkova TL, Synbulatov IV
Article Title: Molecularly imprinted sorbent for biological fluids sample preparation in forensic toxicology (in Russian).
Publication date: 2021
Journal: Sudebno-Meditsinskaya Ekspertisa
Volume: 64
Issue: (6)
Page numbers: 39-42.
DOI: 10.17116/sudmed20216406139
Alternative URL: https://www.mediasphera.ru/issues/sudebno-meditsinskaya-ekspertiza/2021/6/1003945212021061039?clear_cache=Y
Abstract: The objective of this work is to evaluate the possibility of biological fluids sample preparation in forensic toxicology using a molecularly imprinted sorbent based on acrylic acid derivatives. Phenylpiracetam has similar physicochemical properties to those of pyrrolidinophenone derivatives and reproduces their behavior during solid-phase extraction. The phenylpiracetam recovery from blood and urine model samples is 75% for concentration range of 100.0 - 6000.0 ng/ml. The accuracy of phenylpiracetam extraction does not exceed ±12% for blood samples and ±6% for urine samples. The repeatability is no more than 16% and 13% for blood and urine samples, respectively. A study of the cross-reactivity of the molecularly imprinted sorbent with some drugs showed the selectivity of the sample preparation procedure.
Template and target information: phenylpiracetam
Author keywords: Molecularly imprinted sorbents, Solid-phase extraction, phenylpiracetam, metrological characteristics, sample preparation
Join the Society for Molecular Imprinting
New items RSS feed
View latest updatesSign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.
Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
