Alternatively for mipdatabase quick searches go here

Custom Search

ISBN: 2167-0021
Conference information: Proceedings, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII)

Abstract: We present a novel electrochemical biosensing platform for the detection of neurotransmitter glutamate using templated polymer-based target receptors. Our sensing approach demonstrates, for the first time, a nonenzymatic approach without the need of glutamate oxidase, leading to a more specific and rapid response. The proposed detection principle is based on the following two claims: (1) our templated polymer-based receptor results in specific molecular recognition of the target glutamate and, (2) upon target binding, the polymer undergoes a conformation change which can then be measured via electrochemical techniques. This sensing platform has the potential to provide direct monitoring of a variety of nonelectroactive species and to eliminate the incorporation of enzymes thereby providing a simpler and more robust alternative to enzyme-based sensors
Template and target information: glutamate
Author keywords: Non-enzymatic, Biosensing, Templated polymer, electrochemical detection, neurotransmitter, glutamate