Alternatively for mipdatabase quick searches go here

Custom Search

Abstract: Volatile organic compounds are valuable biomarkers for monitoring the metabolic status of cells and even diagnosing diseases, like cancer. Herein, a chemiresistive sensor was developed to detect gaseous nonanal which is one of the biomarkers associated with cancers. Molecularly imprinted polymers (MIPs) and organic solvent-synthesized gold nanoparticles (AuNPs) were combined with a simple process to form a conductive composite as the active layer, which was then drop-casted on the surface of the interdigitated electrodes (IDEs). The conductivity changes that occurred in the presence of the target analyte were measured using a highly accurate potentiostat in a two electrode system. The limit of detection (LOD) and linear range of the sensor were determined as 4.5 ppm and 2.5-100 ppm, respectively. Sensor selectivity was assessed and the analytes were successfully classified using partial least squares discriminant analysis (PLS-DA). The sensor operates at room temperature and is able to detect nonanal in the head space of human plasma in real time mode without the need for pre-concentration
Template and target information: nonanal
Author keywords: Chemiresistive sensor, Volatile organic compound, molecularly imprinted polymer, Nonanal, Gold nanoparticle