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Reference type: Journal
Authors: Guo TY, Zhang LY, Hao GJ, Song MD, Zhang BH
Article Title: Preparation of uniform-sized molecularly imprinted polymer microspheres using N-Cbz-L-Trp as template.
Publication date: 2004
Journal: Chemical Journal of Chinese Universities
Volume: 25
Issue: (4)
Page numbers: 762-765.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-GDXH200404046.htm

Abstract: Uniform-sized molecularly imprinted polymer microspheres were prepared by using N-benzyloxycarbonyl-L-tryptophane(N-Cbz-L- Trp) as the template via a multi-step swelling and suspension polymerization method in which 2-vinylpyridine (2-VP) was used as the functional monomer and diethylene glycol diacrylate (DEGDA) was used as the cross-linker. The surfaces of nonporous micropheres were rough. The average diameter of polymer micropheres was 6.3 mum, and its distribution coeffiene was 1.03. It was found that the baseline chiral separation of the template enantiomer was achieved on a shorter column. Moreover, the removing of the template molecule and the thermal stability of MIP micropheres were also discussed
Template and target information: N-benzyloxycarbonyl-L-tryptophane, N-Cbz-L- Trp


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